This morning I tried for the first time since we use OpenLP to play a DVD. Although the dialog with the preview of the contents showed up it gave an error message that the DVD was not loaded correctly after pressing "save".
I have Windows 10 Pro, build 10586.494, OpenLP 2.4.2 and VLC 2.2.4. VLC is activated as the only player in the settings of OpenLP.
I did a custom install with both DVD playback as all video and audio associations selected.
OpenLP is used by a Windows account without administrative privileges.
Please let me know if you need more information.